KPV
KPV (Lys-Pro-Val) — α-MSH C-terminal tripeptide
The certificate for the current lot isn't published yet. Every lot is third-party tested before it ships.
Research use only — intended for laboratory research. Not for human or veterinary use.
KPV (Lys-Pro-Val) is the C-terminal tripeptide of alpha-melanocyte-stimulating hormone (α-MSH, residues 11–13). It retains much of the anti-inflammatory activity attributed to the full-length hormone in research models, without the pigmentary effects associated with melanocortin-1 receptor activation. Its small size allows uptake into intestinal epithelial and immune cells via the di/tripeptide transporter PepT1, where it has been studied for its ability to dampen NF-κB and MAP-kinase inflammatory signaling. KPV has been a focus of preclinical research into intestinal inflammation, epithelial barrier function, and wound healing.
- Mol. weight
- 342.43
- Purity
- ≥99.0%
- Form
- Lyophilized powder
- Storage
- −20°C, dry, dark
- CAS
- 67727-97-3
- Formula
- C₁₆H₃₀N₄O₄
- Mol. weight
- 342.43
- Purity
- ≥99.0%
- Form
- Lyophilized powder
- PubChem CID
- 125672
Store lyophilized peptide at −20°C, protected from light and moisture. After reconstitution, store at 2–8°C.
KPV (Lys-Pro-Val) is the C-terminal tripeptide of alpha-melanocyte-stimulating hormone (α-MSH, residues 11–13). It retains much of the anti-inflammatory activity attributed to the full-length hormone in research models, without the pigmentary effects associated with melanocortin-1 receptor activation. Its small size allows uptake into intestinal epithelial and immune cells via the di/tripeptide transporter PepT1, where it has been studied for its ability to dampen NF-κB and MAP-kinase inflammatory signaling. KPV has been a focus of preclinical research into intestinal inflammation, epithelial barrier function, and wound healing.
The RAC
standard
QuestionsQuestions
Each vial contains lyophilized peptide powder at the labeled dosage. No solvents, fillers, or preservatives.
Every batch is HPLC-tested. Certificate of Analysis (COA) and HPLC report are available on the product page.
Store the lyophilized peptide at −20°C, dry and dark. See the Storage tab for product-specific details.
United States only, in temperature-controlled packaging. 3–5 day standard or 1–2 day express.
No. All products are for laboratory and research use only (RUO) and are not intended for human or veterinary use.
Research use only. Not for human or veterinary use.
